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The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis

Diet-induced obesity causes chronic macrophage-driven inflammation in white adipose tissue (WAT) leading to insulin resistance. WAT macrophages, however, differ in their origin, gene expression and activities: unlike infiltrating monocyte-derived inflammatory macrophages, WAT-resident macrophages co...

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Detalles Bibliográficos
Autores principales: Coppo, Maddalena, Chinenov, Yurii, Sacta, Maria A., Rogatsky, Inez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974480/
https://www.ncbi.nlm.nih.gov/pubmed/27464507
http://dx.doi.org/10.1038/ncomms12254