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Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity

Plasma cells (PCs) as effectors of humoral immunity produce Igs to match pathogenic insult. Emerging data suggest more diverse roles exist for PCs as regulators of immune and inflammatory responses via secretion of factors other than Igs. The extent to which such responses are preprogrammed in B-lin...

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Detalles Bibliográficos
Autores principales: Care, Matthew A., Stephenson, Sophie J., Barnes, Nicholas A., Fan, Im, Zougman, Alexandre, El-Sherbiny, Yasser M., Vital, Edward M., Westhead, David R., Tooze, Reuben M., Doody, Gina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974491/
https://www.ncbi.nlm.nih.gov/pubmed/27357150
http://dx.doi.org/10.4049/jimmunol.1600624