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Molecular and Genetic Characterization of HIV-1 Tat Exon-1 Gene from Cameroon Shows Conserved Tat HLA-Binding Epitopes: Functional Implications

HIV-1 Tat plays a critical role in viral transactivation. Subtype-B Tat has potential use as a therapeutic vaccine. However, viral genetic diversity and population genetics would significantly impact the efficacy of such a vaccine. Over 70% of the 37-million HIV-infected individuals are in sub-Sahar...

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Detalles Bibliográficos
Autores principales: Teto, Georges, Fonsah, Julius Y., Tagny, Claude T., Mbanya, Dora, Nchindap, Emilienne, Kenmogne, Leopoldine, Fokam, Joseph, Njamnshi, Dora M., Kouanfack, Charles, Njamnshi, Alfred K., Kanmogne, Georgette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974531/
https://www.ncbi.nlm.nih.gov/pubmed/27438849
http://dx.doi.org/10.3390/v8070196