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N-Terminal Domain of Feline Calicivirus (FCV) Proteinase-Polymerase Contributes to the Inhibition of Host Cell Transcription

Feline Calicivirus (FCV) infection results in the inhibition of host protein synthesis, known as “shut-off”. However, the precise mechanism of shut-off remains unknown. Here, we found that the FCV strain 2280 proteinase-polymerase (PP) protein can suppress luciferase reporter gene expression driven...

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Detalles Bibliográficos
Autores principales: Wu, Hongxia, Zu, Shaopo, Sun, Xue, Liu, Yongxiang, Tian, Jin, Qu, Liandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974534/
https://www.ncbi.nlm.nih.gov/pubmed/27447663
http://dx.doi.org/10.3390/v8070199