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Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis

Matrix expansion and cell proliferation are concomitantly observed in various glomerular injuries. However, the molecular mechanisms responsible for these changes have not been fully elucidated. We have reported that Smad1 is a key signalling molecule that regulates the transcription of type IV coll...

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Detalles Bibliográficos
Autores principales: Araki, Makoto, Matsubara, Takeshi, Abe, Hideharu, Torikoshi, Kazuo, Mima, Akira, Iehara, Noriyuki, Fukatsu, Atsushi, Kita, Toru, Arai, Hidenori, Doi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974558/
https://www.ncbi.nlm.nih.gov/pubmed/27492138
http://dx.doi.org/10.1038/srep31216