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Rapid construction of metabolite biosensors using domain-insertion profiling

Single-fluorescent protein biosensors (SFPBs) are an important class of probes that enable the single-cell quantification of analytes in vivo. Despite advantages over other detection technologies, their use has been limited by the inherent challenges of their construction. Specifically, the rational...

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Detalles Bibliográficos
Autores principales: Nadler, Dana C., Morgan, Stacy-Anne, Flamholz, Avi, Kortright, Kaitlyn E., Savage, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974565/
https://www.ncbi.nlm.nih.gov/pubmed/27470466
http://dx.doi.org/10.1038/ncomms12266