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Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes

Neutrophil extracellular traps (NETs) have been implicated in the development of certain immune-mediated diseases, but their role in psoriasis has not been clearly defined. Human β-defensin-2 (HBD-2) is an important antimicrobial peptide overexpressed in psoriasis epidermis. We evaluated whether the...

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Detalles Bibliográficos
Autores principales: Hu, Stephen Chu-Sung, Yu, Hsin-Su, Yen, Feng-Lin, Lin, Chi-Ling, Chen, Gwo-Shing, Lan, Cheng-Che E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974609/
https://www.ncbi.nlm.nih.gov/pubmed/27493143
http://dx.doi.org/10.1038/srep31119