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A distinct sortase SrtB anchors and processes a streptococcal adhesin AbpA with a novel structural property

Surface display of proteins by sortases in Gram-positive bacteria is crucial for bacterial fitness and virulence. We found a unique gene locus encoding an amylase-binding adhesin AbpA and a sortase B in oral streptococci. AbpA possesses a new distinct C-terminal cell wall sorting signal. We demonstr...

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Detalles Bibliográficos
Autores principales: Liang, Xiaobo, Liu, Bing, Zhu, Fan, Scannapieco, Frank A., Haase, Elaine M., Matthews, Steve, Wu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974636/
https://www.ncbi.nlm.nih.gov/pubmed/27492581
http://dx.doi.org/10.1038/srep30966