Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk

Cholesterol 24-hydroxylase (CYP46A1) is responsible for brain cholesterol elimination and therefore plays a crucial role in the control of brain cholesterol homeostasis. Altered CYP46A1 expression has been associated with several neurodegenerative diseases and changes in cognition. Since CYP46A1 act...

Descripción completa

Detalles Bibliográficos
Autores principales: Moutinho, Miguel, Nunes, Maria João, Correia, Jorge C., Gama, Maria João, Castro-Caldas, Margarida, Cedazo-Minguez, Angel, Rodrigues, Cecília M. P., Björkhem, Ingemar, Ruas, Jorge L, Rodrigues, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974659/
https://www.ncbi.nlm.nih.gov/pubmed/27491694
http://dx.doi.org/10.1038/srep30928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974659/
https://www.ncbi.nlm.nih.gov/pubmed/27491694
http://dx.doi.org/10.1038/srep30928

Ejemplares similares