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Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk

Cholesterol 24-hydroxylase (CYP46A1) is responsible for brain cholesterol elimination and therefore plays a crucial role in the control of brain cholesterol homeostasis. Altered CYP46A1 expression has been associated with several neurodegenerative diseases and changes in cognition. Since CYP46A1 act...

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Detalles Bibliográficos
Autores principales:	Moutinho, Miguel, Nunes, Maria João, Correia, Jorge C., Gama, Maria João, Castro-Caldas, Margarida, Cedazo-Minguez, Angel, Rodrigues, Cecília M. P., Björkhem, Ingemar, Ruas, Jorge L, Rodrigues, Elsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974659/ https://www.ncbi.nlm.nih.gov/pubmed/27491694 http://dx.doi.org/10.1038/srep30928

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