A critical role for NF2 and the Hippo pathway in branching morphogenesis

Branching morphogenesis is a complex biological process common to the development of most epithelial organs. Here we demonstrate that NF2, LATS1/2 and YAP play a critical role in branching morphogenesis in the mouse kidney. Removal of Nf2 or Lats1/2 from the ureteric bud (UB) lineage causes loss of...

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Detalles Bibliográficos
Autores principales: Reginensi, Antoine, Enderle, Leonie, Gregorieff, Alex, Johnson, Randy L., Wrana, Jeffrey L., McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974664/
https://www.ncbi.nlm.nih.gov/pubmed/27480037
http://dx.doi.org/10.1038/ncomms12309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974664/
https://www.ncbi.nlm.nih.gov/pubmed/27480037
http://dx.doi.org/10.1038/ncomms12309

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