Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases

STUDY QUESTION: Can spontaneous premature ovarian failure (POF) patients derived from population-based biobanks reveal the association between copy number variations (CNVs) and POF? SUMMARY ANSWER: CNVs can hamper the functional capacity of ovaries by disrupting key genes and pathways essential for...

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Detalles Bibliográficos
Autores principales: Tšuiko, O., Nõukas, M., Žilina, O., Hensen, K., Tapanainen, J.S., Mägi, R., Kals, M., Kivistik, P.A., Haller-Kikkatalo, K., Salumets, A., Kurg, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974666/
https://www.ncbi.nlm.nih.gov/pubmed/27301361
http://dx.doi.org/10.1093/humrep/dew142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974666/
https://www.ncbi.nlm.nih.gov/pubmed/27301361
http://dx.doi.org/10.1093/humrep/dew142

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