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A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells

BACKGROUND: Radioresistant glioblastoma stem cells (GSCs) contribute to tumor recurrence and identification of the molecular targets involved in radioresistance mechanisms is likely to enhance therapeutic efficacy. This study analyzed the DNA damage response following ionizing radiation (IR) in 10 G...

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Detalles Bibliográficos
Autores principales: Balbous, Anaïs, Cortes, Ulrich, Guilloteau, Karline, Rivet, Pierre, Pinel, Baptiste, Duchesne, Mathilde, Godet, Julie, Boissonnade, Odile, Wager, Michel, Bensadoun, René Jean, Chomel, Jean-Claude, Karayan-Tapon, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974671/
https://www.ncbi.nlm.nih.gov/pubmed/27495836
http://dx.doi.org/10.1186/s12885-016-2647-9