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MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression

BACKGROUND: MicroRNA-21 (miR-21) is up-regulated in many cancers, including colorectal cancer (CRC). Nevertheless, the function of miR-21 in CRC and the mechanism underlying that function is still unclear. METHODS: After analyzing the expression of miR-21 and Sec23A in CRC cell lines, we transfected...

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Detalles Bibliográficos
Autores principales: Li, Chenli, Zhao, Lingxu, Chen, Yuan, He, Tiantian, Chen, Xiaowan, Mao, Jiating, Li, Chunmei, Lyu, Jianxin, Meng, Qing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974737/
https://www.ncbi.nlm.nih.gov/pubmed/27495250
http://dx.doi.org/10.1186/s12885-016-2628-z