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MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene

BACKGROUND: Chemoresistance hinders curative cancer chemotherapy in osteosarcoma (OS), resulting in only an approximately 20 % survival rate in patients with metastatic disease at diagnosis. Identifying the mechanisms responsible for regulating chemotherapy resistance is crucial for improving OS tre...

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Detalles Bibliográficos
Autores principales: Pu, Youguang, Yi, Qiyi, Zhao, Fangfang, Wang, Haiyan, Cai, Wenjing, Cai, Shanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974744/
https://www.ncbi.nlm.nih.gov/pubmed/27499703
http://dx.doi.org/10.1186/s12935-016-0340-3