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MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene
BACKGROUND: Chemoresistance hinders curative cancer chemotherapy in osteosarcoma (OS), resulting in only an approximately 20 % survival rate in patients with metastatic disease at diagnosis. Identifying the mechanisms responsible for regulating chemotherapy resistance is crucial for improving OS tre...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974744/ https://www.ncbi.nlm.nih.gov/pubmed/27499703 http://dx.doi.org/10.1186/s12935-016-0340-3 |