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Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

BACKGROUND: Controlled human malaria infection (CHMI) has become well-established in the evaluation of drugs and vaccines. Anti-malarial treatment is usually initiated when thick blood smears are positive by microscopy. This study explores the effects of using the more sensitive qPCR as the primary...

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Detalles Bibliográficos
Autores principales: Walk, Jona, Schats, Remko, Langenberg, Marijke C. C., Reuling, Isaie J., Teelen, Karina, Roestenberg, Meta, Hermsen, Cornelus C., Visser, Leo G., Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974752/
https://www.ncbi.nlm.nih.gov/pubmed/27495296
http://dx.doi.org/10.1186/s12936-016-1434-z