Whole genome sequencing reveals mycobacterial microevolution among concurrent isolates from sputum and blood in HIV infected TB patients

BACKGROUND: In the context of advanced immunosuppression, M. tuberculosis is known to cause detectable mycobacteremia. However, little is known about the intra-patient mycobacterial microevolution and the direction of seeding between the sputum and blood compartments. METHODS: From a diagnostic stud...

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Detalles Bibliográficos
Autores principales: Ssengooba, Willy, de Jong, Bouke C., Joloba, Moses L., Cobelens, Frank G., Meehan, Conor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974755/
https://www.ncbi.nlm.nih.gov/pubmed/27495002
http://dx.doi.org/10.1186/s12879-016-1737-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974755/
https://www.ncbi.nlm.nih.gov/pubmed/27495002
http://dx.doi.org/10.1186/s12879-016-1737-2

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