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Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring

BACKGROUND: Angiotensin-II (Ang II) mediates progression of autosomal-dominant polycystic kidney disease (ADPKD) and other chronic kidney diseases (CKD). However, markers of kidney Ang II activity are lacking. We previously defined 83 Ang II-regulated proteins in vitro, which reflected kidney Ang II...

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Detalles Bibliográficos
Autores principales: Konvalinka, Ana, Batruch, Ihor, Tokar, Tomas, Dimitromanolakis, Apostolos, Reid, Shelby, Song, Xuewen, Pei, York, Drabovich, Andrei P., Diamandis, Eleftherios P., Jurisica, Igor, Scholey, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974759/
https://www.ncbi.nlm.nih.gov/pubmed/27499720
http://dx.doi.org/10.1186/s12014-016-9117-x