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Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

BACKGROUND: Identification of targetable EML4-ALK fusion proteins has revolutionized the treatment of a minor subgroup of non-small cell lung cancer (NSCLC) patients. Although fluorescence in situ hybridization (FISH) is regarded as the gold standard for detection of ALK rearrangements, ALK immunohi...

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Detalles Bibliográficos
Autores principales: Mattsson, Johanna S. M., Brunnström, Hans, Jabs, Verena, Edlund, Karolina, Jirström, Karin, Mindus, Stephanie, la Fleur, Linnéa, Pontén, Fredrik, Karlsson, Mats G., Karlsson, Christina, Koyi, Hirsh, Brandén, Eva, Botling, Johan, Helenius, Gisela, Micke, Patrick, Svensson, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974795/
https://www.ncbi.nlm.nih.gov/pubmed/27495736
http://dx.doi.org/10.1186/s12885-016-2646-x