Cargando…

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

BACKGROUND: Identification of targetable EML4-ALK fusion proteins has revolutionized the treatment of a minor subgroup of non-small cell lung cancer (NSCLC) patients. Although fluorescence in situ hybridization (FISH) is regarded as the gold standard for detection of ALK rearrangements, ALK immunohi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mattsson, Johanna S. M., Brunnström, Hans, Jabs, Verena, Edlund, Karolina, Jirström, Karin, Mindus, Stephanie, la Fleur, Linnéa, Pontén, Fredrik, Karlsson, Mats G., Karlsson, Christina, Koyi, Hirsh, Brandén, Eva, Botling, Johan, Helenius, Gisela, Micke, Patrick, Svensson, Maria A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974795/ https://www.ncbi.nlm.nih.gov/pubmed/27495736 http://dx.doi.org/10.1186/s12885-016-2646-x

Ejemplares similares

Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non‐small cell lung cancer
por: Salomonsson, Annette, et al.
Publicado: (2020)

Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer
por: Micke, Patrick, et al.
Publicado: (2019)

Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas
por: Thurfjell, Viktoria, et al.
Publicado: (2022)

PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung
por: Goldmann, Torsten, et al.
Publicado: (2021)

A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer
por: Karlsson, Anna, et al.
Publicado: (2019)

Loss of glutathione peroxidase 3 expression is correlated with epigenetic mechanisms in endometrial adenocarcinoma
por: Falck, Eva, et al.
Publicado: (2010)

A protocol for a prospective observational study using chest and thumb ECG: transient ECG assessment in stroke evaluation (TEASE) in Sweden
por: Magnusson, Peter, et al.
Publicado: (2018)

Viral Load, Integration and Methylation of E2BS3 and 4 in Human Papilloma Virus (HPV) 16-Positive Vaginal and Vulvar Carcinomas
por: Lillsunde Larsson, Gabriella, et al.
Publicado: (2014)

HPV-based screening for cervical cancer among women 55-59 years of age
por: Bergengren, Lovisa, et al.
Publicado: (2019)

Identification of sample annotation errors in gene expression datasets
por: Lohr, Miriam, et al.
Publicado: (2015)

Computer tomography-guided core biopsies in a county hospital in Sweden: Complication rate and diagnostic yield
por: Brandén, Eva, et al.
Publicado: (2014)

Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to EGFR and KRAS Mutation Status
por: Planck, Maria, et al.
Publicado: (2013)

Case Report: ALK rearranged locally advanced lung adenocarcinoma showing inconsistent radiographic findings and pathological responses during neoadjuvant alectinib therapy
por: Cao, Peijun, et al.
Publicado: (2023)

Does p53 codon 72 polymorphism have a prognostic value in carcinoma of the vulva and vagina?
por: Qvick, Alvida, et al.
Publicado: (2017)

HPV16 viral characteristics in primary, recurrent and metastatic vulvar carcinoma
por: Lillsunde Larsson, Gabriella, et al.
Publicado: (2018)

Full genotyping and FAM19A4/miR124-2 methylation analysis in high-risk human papillomavirus–positive samples from women over 30 years participating in cervical cancer screening in Örebro, Sweden
por: Kaliff, Malin, et al.
Publicado: (2022)

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer
por: Jabs, Verena, et al.
Publicado: (2017)

KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice
por: Sundström, Magnus, et al.
Publicado: (2010)

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics
por: Grundberg, Ida, et al.
Publicado: (2013)

Impact of ALK Inhibitors in Patients With ALK-Rearranged Nonlung Solid Tumors
por: Takeyasu, Yuki, et al.
Publicado: (2021)

Differences in microRNA expression during tumor development in the transition and peripheral zones of the prostate
por: Carlsson, Jessica, et al.
Publicado: (2013)

Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ
por: Mignardi, Marco, et al.
Publicado: (2015)

A gene expression‐based single sample predictor of lung adenocarcinoma molecular subtype and prognosis
por: Liljedahl, Helena, et al.
Publicado: (2020)

Clinical outcomes in ALK-rearranged lung adenocarcinomas according to ALK fusion variants
por: Cha, Yoon Jin, et al.
Publicado: (2016)

Findings of multiple HPV genotypes in cervical carcinoma are associated with poor cancer-specific survival in a Swedish cohort of cervical cancer primarily treated with radiotherapy
por: Kaliff, Malin, et al.
Publicado: (2018)

HPV-negative Tumors in a Swedish Cohort of Cervical Cancer
por: Kaliff, Malin, et al.
Publicado: (2020)

Effectiveness and costs of an implemented primary HPV cervical screening programme in Sweden – A population based cohort study
por: Bergengren, Lovisa, et al.
Publicado: (2021)

ALK-rearranged squamous cell carcinoma of the lung
por: Takanashi, Yusuke, et al.
Publicado: (2015)

Endometrial cancer with an EML4-ALK rearrangement
por: Craig, Jeffrey W., et al.
Publicado: (2018)

ALK‐rearranged squamous cell carcinoma of the lung
por: Meng, Qiyi, et al.
Publicado: (2021)

Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes
por: Tang, Zhenya, et al.
Publicado: (2020)

Chemotherapy Treatment of Elderly Patients (≥70 Years) with Non-Small Cell Lung Cancer: A Seven-Year Retrospective Study of Real-Life Clinical Practice at Karolinska University Hospital, Sweden
por: Koyi, Hirsh, et al.
Publicado: (2015)

Screening of ROS1 Rearrangements in Lung Adenocarcinoma by Immunohistochemistry and Comparison with ALK Rearrangements
por: Cha, Yoon Jin, et al.
Publicado: (2014)

Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK‐rearranged lung cancer
por: Yun, Mi Ran, et al.
Publicado: (2019)

Overview of ALK and ROS1 Rearranged Lung Cancer
por: Choi, Chang Min
Publicado: (2013)

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer
por: Mizuta, Hayato, et al.
Publicado: (2021)

Targeting ALK Rearrangements in NSCLC: Current State of the Art
por: Peng, Ling, et al.
Publicado: (2022)

Current status and challenges of immunotherapy in ALK rearranged NSCLC
por: Qi, Rongbin, et al.
Publicado: (2022)

A miRNA expression signature that separates between normal and malignant prostate tissues
por: Carlsson, Jessica, et al.
Publicado: (2011)

Atypical Carcinoid Tumor with Anaplastic Lymphoma Kinase (ALK) Rearrangement Successfully Treated by an ALK Inhibitor
por: Nakajima, Masayuki, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_851khsrl8ie2hvqjdksqbli0qb