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Engineering a light-controlled F(1) ATPase using structure-based protein design
The F(1) sub-complex of ATP synthase is a biological nanomotor that converts the free energy of ATP hydrolysis into mechanical work with an astonishing efficiency of up to 100% (Kinosita et al., 2000). To probe the principal mechanics of the machine, I re-engineered the active site of E.coli F(1) AT...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PeerJ Inc.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974930/ https://www.ncbi.nlm.nih.gov/pubmed/27547581 http://dx.doi.org/10.7717/peerj.2286 |