Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients

We investigated whether circulating osteopontin (OPN) could be used as a biomarker for cervical cancer. We employed a monoclonal antibody (mAb 659) specific for the unique and intact thrombin-sensitive site in OPN using an inhibition ELISA. We found significantly higher levels of OPN in 33 cervical...

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Detalles Bibliográficos
Autores principales: Leung, Danny T. M., Lim, Pak-Leong, Cheung, Tak-Hong, Wong, Raymond R. Y., Yim, So-Fan, Ng, Margaret H. L., Tam, Frankie C. H., Chung, Tony K. H., Wong, Yick-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975440/
https://www.ncbi.nlm.nih.gov/pubmed/27494141
http://dx.doi.org/10.1371/journal.pone.0160412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975440/
https://www.ncbi.nlm.nih.gov/pubmed/27494141
http://dx.doi.org/10.1371/journal.pone.0160412

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