Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive disease with poor survival rates and limited treatment options. Upregulation of αvβ6 integrins within the alveolar epithelial cells is a characteristic feature of IPF and correlates with poor patient survival. The pro-fibrotic cytokin...

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Detalles Bibliográficos
Autores principales: Tatler, Amanda L., Goodwin, Amanda T., Gbolahan, Olumide, Saini, Gauri, Porte, Joanne, John, Alison E., Clifford, Rachel L., Violette, Shelia M., Weinreb, Paul H., Parfrey, Helen, Wolters, Paul J., Gauldie, Jack, Kolb, Martin, Jenkins, Gisli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975449/
https://www.ncbi.nlm.nih.gov/pubmed/27494713
http://dx.doi.org/10.1371/journal.pone.0158047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975449/
https://www.ncbi.nlm.nih.gov/pubmed/27494713
http://dx.doi.org/10.1371/journal.pone.0158047

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