Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2

We combined two tuberculosis (TB) genome-wide association studies (GWAS) from Ghana and The Gambia with subsequent replication totalling 11,425 participants. A significant association with disease was observed at SNP rs4331426 located in a gene-poor region on chromosome 18q11.2 (P=6.8×10(−9), OR=1.1...

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Detalles Bibliográficos
Autores principales: Thye, Thorsten, Vannberg, Fredrik O., Wong, Sunny H., Owusu-Dabo, Ellis, Osei, Ivy, Gyapong, John, Sirugo, Giorgio, Sisay-Joof, Fatou, Enimil, Anthony, Chinbuah, Margaret A., Floyd, Sian, Warndorff, David K., Sichali, Lifted, Malema, Simon, Crampin, Amelia C., Ngwira, Bagrey, Teo, Yik Y., Small, Kerrin, Rockett, Kirk, Kwiatkowski, Dominic, Fine, Paul E., Hill, Philip C., Newport, Melanie, Lienhardt, Christian, Adegbola, Richard A., Corrah, Tumani, Ziegler, Andreas, Morris, Andrew P., Meyer, Christian G., Horstmann, Rolf D., Hill, Adrian V.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975513/
https://www.ncbi.nlm.nih.gov/pubmed/20694014
http://dx.doi.org/10.1038/ng.639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975513/
https://www.ncbi.nlm.nih.gov/pubmed/20694014
http://dx.doi.org/10.1038/ng.639

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