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POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

Mitochondria are vital in providing cellular energy via their oxidative phosphorylation system, which requires the coordinated expression of genes encoded by both the nuclear and mitochondrial genomes (mtDNA). Transcription of the circular mammalian mtDNA depends on a single mitochondrial RNA polyme...

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Detalles Bibliográficos
Autores principales: Kühl, Inge, Miranda, Maria, Posse, Viktor, Milenkovic, Dusanka, Mourier, Arnaud, Siira, Stefan J., Bonekamp, Nina A., Neumann, Ulla, Filipovska, Aleksandra, Polosa, Paola Loguercio, Gustafsson, Claes M., Larsson, Nils-Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975551/
https://www.ncbi.nlm.nih.gov/pubmed/27532055
http://dx.doi.org/10.1126/sciadv.1600963