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A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense

Humans are protected against infection from most African trypanosomes by lipoprotein complexes present in serum that contain the trypanolytic pore-forming protein, Apolipoprotein L1 (APOL1). The human-infective trypanosomes, Trypanosoma brucei rhodesiense in East Africa and T. b. gambiense in West A...

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Detalles Bibliográficos
Autores principales: Cooper, Anneli, Capewell, Paul, Clucas, Caroline, Veitch, Nicola, Weir, William, Thomson, Russell, Raper, Jayne, MacLeod, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975595/
https://www.ncbi.nlm.nih.gov/pubmed/27494254
http://dx.doi.org/10.1371/journal.pntd.0004903