Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics

The reactive dicarbonyl metabolite methylglyoxal (MG) is the precursor of the major quantitative advanced glycation endproducts (AGEs) in physiological systems - arginine-derived hydroimidazolones and deoxyguanosine-derived imidazopurinones. The glyoxalase system in the cytoplasm of cells provides t...

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Detalles Bibliográficos
Autores principales: Rabbani, Naila, Xue, Mingzhan, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975768/
https://www.ncbi.nlm.nih.gov/pubmed/27406712
http://dx.doi.org/10.1007/s10719-016-9705-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975768/
https://www.ncbi.nlm.nih.gov/pubmed/27406712
http://dx.doi.org/10.1007/s10719-016-9705-z

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