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Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
The reactive dicarbonyl metabolite methylglyoxal (MG) is the precursor of the major quantitative advanced glycation endproducts (AGEs) in physiological systems - arginine-derived hydroimidazolones and deoxyguanosine-derived imidazopurinones. The glyoxalase system in the cytoplasm of cells provides t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975768/ https://www.ncbi.nlm.nih.gov/pubmed/27406712 http://dx.doi.org/10.1007/s10719-016-9705-z |