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Treatment of patients with aortic atherosclerotic disease with paclitaxel-associated lipid nanoparticles

OBJECTIVE: The toxicity of anti-cancer chemotherapeutic agents can be reduced by associating these compounds, such as the anti-proliferative agent paclitaxel, with a cholesterol-rich nanoemulsion (LDE) that mimics the lipid composition of low-density lipoprotein (LDL). When injected into circulation...

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Detalles Bibliográficos
Autores principales: Shiozaki, Afonso A., Senra, Tiago, Morikawa, Aleksandra T., Deus, Débora F., Paladino, Antonio T, Pinto, Ibraim M.F., Maranhão, Raul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975788/
https://www.ncbi.nlm.nih.gov/pubmed/27626473
http://dx.doi.org/10.6061/clinics/2016(08)05