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Hedgehog Signalling in the Embryonic Mouse Thymus

T cells develop in the thymus, which provides an essential environment for T cell fate specification, and for the differentiation of multipotent progenitor cells into major histocompatibility complex (MHC)-restricted, non-autoreactive T cells. Here we review the role of the Hedgehog signalling pathw...

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Detalles Bibliográficos
Autores principales: Barbarulo, Alessandro, Lau, Ching-In, Mengrelis, Konstantinos, Ross, Susan, Solanki, Anisha, Saldaña, José Ignacio, Crompton, Tessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975939/
https://www.ncbi.nlm.nih.gov/pubmed/27504268
http://dx.doi.org/10.3390/jdb4030022