Cargando…
Hedgehog Signalling in the Embryonic Mouse Thymus
T cells develop in the thymus, which provides an essential environment for T cell fate specification, and for the differentiation of multipotent progenitor cells into major histocompatibility complex (MHC)-restricted, non-autoreactive T cells. Here we review the role of the Hedgehog signalling pathw...
Autores principales: | Barbarulo, Alessandro, Lau, Ching-In, Mengrelis, Konstantinos, Ross, Susan, Solanki, Anisha, Saldaña, José Ignacio, Crompton, Tessa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975939/ https://www.ncbi.nlm.nih.gov/pubmed/27504268 http://dx.doi.org/10.3390/jdb4030022 |
Ejemplares similares
-
Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus
por: Mengrelis, Konstantinos, et al.
Publicado: (2019) -
The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus
por: Lau, Ching-In, et al.
Publicado: (2017) -
Sonic Hedgehog regulates thymic epithelial cell differentiation
por: Saldaña, José Ignacio, et al.
Publicado: (2016) -
The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity
por: Furmanski, Anna L., et al.
Publicado: (2015) -
A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation
por: Sahni, Hemant, et al.
Publicado: (2015)