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Multifaceted Role of Sialylation in Prion Diseases

Mammalian prion or PrP(Sc) is a proteinaceous infectious agent that consists of a misfolded, self-replicating state of a sialoglycoprotein called the prion protein, or PrP(C). Sialylation of the prion protein N-linked glycans was discovered more than 30 years ago, yet the role of sialylation in prio...

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Detalles Bibliográficos
Autores principales: Baskakov, Ilia V., Katorcha, Elizaveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976111/
https://www.ncbi.nlm.nih.gov/pubmed/27551257
http://dx.doi.org/10.3389/fnins.2016.00358