Cargando…
Multifaceted Role of Sialylation in Prion Diseases
Mammalian prion or PrP(Sc) is a proteinaceous infectious agent that consists of a misfolded, self-replicating state of a sialoglycoprotein called the prion protein, or PrP(C). Sialylation of the prion protein N-linked glycans was discovered more than 30 years ago, yet the role of sialylation in prio...
Autores principales: | Baskakov, Ilia V., Katorcha, Elizaveta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976111/ https://www.ncbi.nlm.nih.gov/pubmed/27551257 http://dx.doi.org/10.3389/fnins.2016.00358 |
Ejemplares similares
-
Sialylation of the prion protein glycans controls prion replication rate and glycoform ratio
por: Katorcha, Elizaveta, et al.
Publicado: (2015) -
Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP(Sc) Glycoform and Prion Infectivity
por: Katorcha, Elizaveta, et al.
Publicado: (2014) -
Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation
por: Katorcha, Elizaveta, et al.
Publicado: (2016) -
Inflammatory response of microglia to prions is controlled by sialylation of PrP(Sc)
por: Srivastava, Saurabh, et al.
Publicado: (2018) -
Prion Strain-Specific Structure and Pathology: A View from the Perspective of Glycobiology
por: Baskakov, Ilia V., et al.
Publicado: (2018)