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Upregulation of TSHR, TTF-1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen

Objective. It has been testified that iodine regulates thyroid function by controlling thyroid-restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction. However, the effects of follicular lumen iodine, the main form of iodine reserve in the body, on thyroid-restri...

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Detalles Bibliográficos
Autores principales: Huang, Huibin, Chen, Lijun, Liang, Bo, Cai, Huiyao, Cai, Qingyan, Shi, Yaxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976194/
https://www.ncbi.nlm.nih.gov/pubmed/27525008
http://dx.doi.org/10.1155/2016/2492450