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Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro

Most sub-cellular cargos are transported along microtubules by kinesin and dynein molecular motors, but how transport is regulated is not well understood. It is unknown whether local control is possible, for example, by changes in specific cargo-associated motor behaviour to react to impediments. He...

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Detalles Bibliográficos
Autores principales: Reddy, Babu J. N., Mattson, Michelle, Wynne, Caitlin L., Vadpey, Omid, Durra, Abdo, Chapman, Dail, Vallee, Richard B., Gross, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976208/
https://www.ncbi.nlm.nih.gov/pubmed/27489054
http://dx.doi.org/10.1038/ncomms12259