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Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro
Most sub-cellular cargos are transported along microtubules by kinesin and dynein molecular motors, but how transport is regulated is not well understood. It is unknown whether local control is possible, for example, by changes in specific cargo-associated motor behaviour to react to impediments. He...
Autores principales: | Reddy, Babu J. N., Mattson, Michelle, Wynne, Caitlin L., Vadpey, Omid, Durra, Abdo, Chapman, Dail, Vallee, Richard B., Gross, Steven P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976208/ https://www.ncbi.nlm.nih.gov/pubmed/27489054 http://dx.doi.org/10.1038/ncomms12259 |
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