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Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

Stem cells are regulated both intrinsically and externally, including by signals from the local environment and distant organs. To identify genes and pathways that regulate stem-cell fates in the whole organism, we perform a genome-wide transgenic RNAi screen through ubiquitous gene knockdowns, focu...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Ge, Qinglan, Chan, Brian, Liu, Hanhan, Singh, Shree Ram, Manley, Jacob, Lee, Jae, Weideman, Ann Marie, Hou, Gerald, Hou, Steven X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976209/
https://www.ncbi.nlm.nih.gov/pubmed/27484291
http://dx.doi.org/10.1038/ncomms12149