Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

Tissue homeostasis is dependent on the controlled localization of specific cell types and the correct composition of the extracellular stroma. While the role of the cancer stroma in tumour progression has been well characterized, the specific contribution of the matrix itself is unknown. Furthermore...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaukonen, Riina, Mai, Anja, Georgiadou, Maria, Saari, Markku, De Franceschi, Nicola, Betz, Timo, Sihto, Harri, Ventelä, Sami, Elo, Laura, Jokitalo, Eija, Westermarck, Jukka, Kellokumpu-Lehtinen, Pirkko-Liisa, Joensuu, Heikki, Grenman, Reidar, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976218/
https://www.ncbi.nlm.nih.gov/pubmed/27488962
http://dx.doi.org/10.1038/ncomms12237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976218/
https://www.ncbi.nlm.nih.gov/pubmed/27488962
http://dx.doi.org/10.1038/ncomms12237

Ejemplares similares