Preventive effect of sildenafil on right ventricular function in rats with monocrotaline-induced pulmonary arterial hypertension

The present study aimed to evaluate the preventive effect of sildenafil treatment on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats. Fifty-four 12-week-old male Sprague–Dawley rats were injected with MCT or saline solution (MCT-injected rats: n=36; saline: n=18). Serial echocardi...

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Detalles Bibliográficos
Autores principales: Yoshiyuki, Rieko, Tanaka, Ryo, Fukushima, Ryuji, Machida, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976235/
https://www.ncbi.nlm.nih.gov/pubmed/26876436
http://dx.doi.org/10.1538/expanim.15-0070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976235/
https://www.ncbi.nlm.nih.gov/pubmed/26876436
http://dx.doi.org/10.1538/expanim.15-0070

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