MtDNA analysis reveals enriched pathogenic mutations in Tibetan highlanders

Tibetan highlanders, including Tibetans, Monpas, Lhobas, Dengs and Sherpas, are considered highly adaptive to severe hypoxic environments. Mitochondrial DNA (mtDNA) might be important in hypoxia adaptation given its role in coding core subunits of oxidative phosphorylation. In this study, we employe...

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Detalles Bibliográficos
Autores principales: Kang, Longli, Zheng, Hong-Xiang, Zhang, Menghan, Yan, Shi, Li, Lei, Liu, Lijun, Liu, Kai, Hu, Kang, Chen, Feng, Ma, Lifeng, Qin, Zhendong, Wang, Yi, Wang, Xiaofeng, Jin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976311/
https://www.ncbi.nlm.nih.gov/pubmed/27498855
http://dx.doi.org/10.1038/srep31083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976311/
https://www.ncbi.nlm.nih.gov/pubmed/27498855
http://dx.doi.org/10.1038/srep31083

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