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Targeted alternative splicing of TAF4: a new strategy for cell reprogramming

Reprogramming of somatic cells has become a versatile tool for biomedical research and for regenerative medicine. In the current study, we show that manipulating alternative splicing (AS) is a highly potent strategy to produce cells for therapeutic applications. We demonstrate that silencing of hTAF...

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Detalles Bibliográficos
Autores principales: Kazantseva, Jekaterina, Sadam, Helle, Neuman, Toomas, Palm, Kaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976350/
https://www.ncbi.nlm.nih.gov/pubmed/27499390
http://dx.doi.org/10.1038/srep30852