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Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in rats

Radiation therapy is commonly used to treat cancer patients but exhibits adverse effects, including insufficiency fractures and bone loss. Epigenetic regulation plays an important role in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Here, we reported local bone changes a...

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Detalles Bibliográficos
Autores principales: Guo, Changjun, Li, Changwei, Yang, Kai, Kang, Hui, Xu, Xiaoya, Xu, Xiangyang, Deng, Lianfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976370/
https://www.ncbi.nlm.nih.gov/pubmed/27499068
http://dx.doi.org/10.1038/srep31318