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Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in rats
Radiation therapy is commonly used to treat cancer patients but exhibits adverse effects, including insufficiency fractures and bone loss. Epigenetic regulation plays an important role in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Here, we reported local bone changes a...
Autores principales: | Guo, Changjun, Li, Changwei, Yang, Kai, Kang, Hui, Xu, Xiaoya, Xu, Xiangyang, Deng, Lianfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976370/ https://www.ncbi.nlm.nih.gov/pubmed/27499068 http://dx.doi.org/10.1038/srep31318 |
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