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Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

Fibroblast growth factor 21 (FGF21) is a hepatokine that regulates glucose and lipid metabolism in the liver. We sought to determine the role of FGF21 in hepatic steatosis in mice exposed to chronic alcohol treatment and to discern underlying mechanisms. Male FGF21 knockout (FGF21 KO) and control (W...

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Detalles Bibliográficos
Autores principales: Liu, Yanlong, Zhao, Cuiqing, Xiao, Jian, Liu, Liming, Zhang, Min, Wang, Cuiling, Wu, Guicheng, Zheng, Ming-Hua, Xu, Lan-Man, Chen, Yong-Ping, Mohammadi, Moosa, Chen, Shao-Yu, Cave, Matthew, McClain, Craig, Li, Xiaokun, Feng, Wenke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976373/
https://www.ncbi.nlm.nih.gov/pubmed/27498701
http://dx.doi.org/10.1038/srep31026