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Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease

BACKGROUND: Amyloid β (Aβ) has been established as a key factor for the pathological changes in the brains of patients with Alzheimer's disease (AD), and cellular senescence is closely associated with aging and cognitive impairment. However, it remains blurred whether, in the AD brains, Aβ acce...

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Detalles Bibliográficos
Autores principales: Wei, Zhen, Chen, Xiao-Chun, Song, Yue, Pan, Xiao-Dong, Dai, Xiao-Man, Zhang, Jing, Cui, Xiao-Li, Wu, Xi-Lin, Zhu, Yuan-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976573/
https://www.ncbi.nlm.nih.gov/pubmed/27453234
http://dx.doi.org/10.4103/0366-6999.186646