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Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease
BACKGROUND: Amyloid β (Aβ) has been established as a key factor for the pathological changes in the brains of patients with Alzheimer's disease (AD), and cellular senescence is closely associated with aging and cognitive impairment. However, it remains blurred whether, in the AD brains, Aβ acce...
Autores principales: | Wei, Zhen, Chen, Xiao-Chun, Song, Yue, Pan, Xiao-Dong, Dai, Xiao-Man, Zhang, Jing, Cui, Xiao-Li, Wu, Xi-Lin, Zhu, Yuan-Gui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976573/ https://www.ncbi.nlm.nih.gov/pubmed/27453234 http://dx.doi.org/10.4103/0366-6999.186646 |
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