Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy

Glial cells efficiently recognize and clear cellular debris after nervous system injury to maintain brain homeostasis, but pathways governing glial responses to neural injury remain poorly defined. We identify the Drosophila guanine-nucleotide exchange factor (GEF) complex Crk/Mbc/dCed-12, and the s...

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Detalles Bibliográficos
Autores principales: Ziegenfuss, Jennifer S., Doherty, Johnna, Freeman, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976689/
https://www.ncbi.nlm.nih.gov/pubmed/22706267
http://dx.doi.org/10.1038/nn.3135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976689/
https://www.ncbi.nlm.nih.gov/pubmed/22706267
http://dx.doi.org/10.1038/nn.3135

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