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Is Transthyretin a Regulator of Ubc9 SUMOylation?

Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...

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Detalles Bibliográficos
Autores principales: Wieczorek, Elżbieta, Kędracka–Krok, Sylwia, Sołtys, Katarzyna, Jankowska, Urszula, Hołubowicz, Rafał, Seliga, Justyna, Ożyhar, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976990/
https://www.ncbi.nlm.nih.gov/pubmed/27501389
http://dx.doi.org/10.1371/journal.pone.0160536