Secreted Phosphoprotein 1 and Sex-Specific Differences in Silica-Induced Pulmonary Fibrosis in Mice

BACKGROUND: Fibrotic lung diseases occur predominantly in males, and reports describe better survival in affected females. Male mice are more sensitive to silica-induced lung fibrosis than silica-treated female mice. Secreted phosphoprotein 1 (SPP1, also known as osteopontin) increases in pulmonary...

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Detalles Bibliográficos
Autores principales: Latoche, Joseph D., Ufelle, Alexander Chukwuma, Fazzi, Fabrizio, Ganguly, Koustav, Leikauf, George D., Fattman, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977050/
https://www.ncbi.nlm.nih.gov/pubmed/26955063
http://dx.doi.org/10.1289/ehp.1510335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977050/
https://www.ncbi.nlm.nih.gov/pubmed/26955063
http://dx.doi.org/10.1289/ehp.1510335

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